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Novel Transcriptional and Translational Biomarkers of Tularemia Vaccine Efficacy in a Mouse Inhalation Model: Proof of Concept
Francisella tularensis subspecies tularensis (Ftt) is extremely virulent for humans when inhaled as a small particle aerosol (<5 µm). Inhalation of ≥20 viable bacteria is sufficient to initiate infection with a mortality rate ≥30%. Consequently, in the past, Ftt became a primary candidate for bio...
Autores principales: | Liu, Qing Yan, Leclerc, Sonia, Pan, Youlian, Liu, Ziying, Stark, Felicity, Conlan, Joseph Wayne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778127/ https://www.ncbi.nlm.nih.gov/pubmed/35056485 http://dx.doi.org/10.3390/microorganisms10010036 |
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