In Silico Design, Synthesis, and Biological Evaluation of Anticancer Arylsulfonamide Endowed with Anti-Telomerase Activity

Telomerase, a reverse transcriptase enzyme involved in DNA synthesis, has a tangible role in tumor progression. Several studies have evidenced telomerase as a promising target for developing cancer therapeutics. The main reason is due to the overexpression of telomerase in cancer cells (85–90%) comp...

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Detalles Bibliográficos
Autores principales: Culletta, Giulia, Allegra, Mario, Almerico, Anna Maria, Restivo, Ignazio, Tutone, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778141/
https://www.ncbi.nlm.nih.gov/pubmed/35056139
http://dx.doi.org/10.3390/ph15010082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778141/
https://www.ncbi.nlm.nih.gov/pubmed/35056139
http://dx.doi.org/10.3390/ph15010082

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