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In Silico Design, Synthesis, and Biological Evaluation of Anticancer Arylsulfonamide Endowed with Anti-Telomerase Activity

Telomerase, a reverse transcriptase enzyme involved in DNA synthesis, has a tangible role in tumor progression. Several studies have evidenced telomerase as a promising target for developing cancer therapeutics. The main reason is due to the overexpression of telomerase in cancer cells (85–90%) comp...

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Detalles Bibliográficos
Autores principales:	Culletta, Giulia, Allegra, Mario, Almerico, Anna Maria, Restivo, Ignazio, Tutone, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778141/ https://www.ncbi.nlm.nih.gov/pubmed/35056139 http://dx.doi.org/10.3390/ph15010082

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