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A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread

The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains within it remain largely uncharacterised. Here, we...

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Detalles Bibliográficos
Autores principales: Snetkov, Xenia, Haider, Tafhima, Mesner, Dejan, Groves, Nicholas, van Engelenburg, Schuyler B., Jolly, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778169/
https://www.ncbi.nlm.nih.gov/pubmed/35062333
http://dx.doi.org/10.3390/v14010129