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A New Oxygen Containing Pyclen-Type Ligand as a Manganese(II) Binder for MRI and (52)Mn PET Applications: Equilibrium, Kinetic, Relaxometric, Structural and Radiochemical Studies

A new pyclen-3,9-diacetate derivative ligand (H(2)3,9-OPC2A) was synthesized possessing an etheric O-atom opposite to the pyridine ring, to improve the dissociation kinetics of its Mn(II) complex (pyclen = 3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15),11,13-triene). The new ligand is less basic tha...

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Detalles Bibliográficos
Autores principales: Csupász, Tibor, Szücs, Dániel, Kálmán, Ferenc Krisztián, Hollóczki, Oldamur, Fekete, Anikó, Szikra, Dezső, Tóth, Éva, Tóth, Imre, Tircsó, Gyula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778187/
https://www.ncbi.nlm.nih.gov/pubmed/35056686
http://dx.doi.org/10.3390/molecules27020371