Formulation, Characterization, and Cytotoxicity Evaluation of Lactoferrin Functionalized Lipid Nanoparticles for Riluzole Delivery to the Brain

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a very poor prognosis. Its treatment is hindered by a lack of new therapeutic alternatives and the existence of the blood–brain barrier (BBB), which restricts the access of drugs commonly used in ALS, such as riluzole, to the br...

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Detalles Bibliográficos
Autores principales: Teixeira, Maria Inês, Lopes, Carla Martins, Gonçalves, Hugo, Catita, José, Silva, Ana Margarida, Rodrigues, Francisca, Amaral, Maria Helena, Costa, Paulo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778224/
https://www.ncbi.nlm.nih.gov/pubmed/35057079
http://dx.doi.org/10.3390/pharmaceutics14010185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778224/
https://www.ncbi.nlm.nih.gov/pubmed/35057079
http://dx.doi.org/10.3390/pharmaceutics14010185

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