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Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives

Imidazolidine and thiazolidine-based isatin derivatives (IST-01–04) were synthesized, characterized, and tested for their interactions with ds-DNA. Theoretical and experimental findings showed good compatibility and indicated compound–DNA binding by mixed mode of interactions. The evaluated binding...

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Detalles Bibliográficos
Autores principales: Arshad, Nasima, Mir, Muhammad Ismail, Perveen, Fouzia, Javed, Aneela, Javaid, Memona, Saeed, Aamer, Channar, Pervaiz Ali, Farooqi, Shahid Iqbal, Alkahtani, Saad, Anwar, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778244/
https://www.ncbi.nlm.nih.gov/pubmed/35056668
http://dx.doi.org/10.3390/molecules27020354