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Relaxed Substrate Specificity in Qβ Replicase through Long-Term In Vitro Evolution
A change from RNA- to DNA-based genetic systems is hypothesized as a major transition in the evolution of early life forms. One of the possible requirements for this transition is a change in the substrate specificity of the replication enzyme. It is largely unknown how such changes would have occur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778257/ https://www.ncbi.nlm.nih.gov/pubmed/35054425 http://dx.doi.org/10.3390/life12010032 |