An Innovative Formulation Based on Nanostructured Lipid Carriers for Imatinib Delivery: Pre-Formulation, Cellular Uptake and Cytotoxicity Studies

Imatinib (IMT) is a tyrosine kinase enzyme inhibitor and extensively used for the treatment of gastrointestinal stromal tumors (GISTs). A nanostructured lipid carrier system (NLCS) containing IMT was developed by using emulsification–sonication methods. The characterization of the developed formulat...

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Detalles Bibliográficos
Autores principales: Gundogdu, Evren, Demir, Emine-Selin, Ekinci, Meliha, Ozgenc, Emre, Ilem-Ozdemir, Derya, Senyigit, Zeynep, Gonzalez-Alvarez, Isabel, Bermejo, Marival
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778264/
https://www.ncbi.nlm.nih.gov/pubmed/35055267
http://dx.doi.org/10.3390/nano12020250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778264/
https://www.ncbi.nlm.nih.gov/pubmed/35055267
http://dx.doi.org/10.3390/nano12020250

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