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An Innovative Formulation Based on Nanostructured Lipid Carriers for Imatinib Delivery: Pre-Formulation, Cellular Uptake and Cytotoxicity Studies
Imatinib (IMT) is a tyrosine kinase enzyme inhibitor and extensively used for the treatment of gastrointestinal stromal tumors (GISTs). A nanostructured lipid carrier system (NLCS) containing IMT was developed by using emulsification–sonication methods. The characterization of the developed formulat...
Autores principales: | Gundogdu, Evren, Demir, Emine-Selin, Ekinci, Meliha, Ozgenc, Emre, Ilem-Ozdemir, Derya, Senyigit, Zeynep, Gonzalez-Alvarez, Isabel, Bermejo, Marival |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778264/ https://www.ncbi.nlm.nih.gov/pubmed/35055267 http://dx.doi.org/10.3390/nano12020250 |
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