Novel Disulfiram Derivatives as ALDH1a1-Selective Inhibitors

Aldehyde dehydrogenase-1a1 (ALDH1a1), the enzyme responsible for the oxidation of retinal into retinoic acid, represents a key therapeutic target for the treatment of debilitating disorders such as cancer, obesity, and inflammation. Drugs that can inhibit ALDH1a1 include disulfiram, an FDA-approved...

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Detalles Bibliográficos
Autor principal: Omran, Ziad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778300/
https://www.ncbi.nlm.nih.gov/pubmed/35056791
http://dx.doi.org/10.3390/molecules27020480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778300/
https://www.ncbi.nlm.nih.gov/pubmed/35056791
http://dx.doi.org/10.3390/molecules27020480

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