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Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Glimepiride is characterized by an inconsistent dissolution and absorption profile due to its limited aqueous solubility. The aim of this study was to develop glimepiride tablets using three different manufacturing techniques, as well as to study their quality attributes and pharmacokinetics behavio...

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Detalles Bibliográficos
Autores principales: Ahmed, Tarek A., Alotaibi, Hanadi A., Alharbi, Waleed S., Safo, Martin K., El-Say, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778328/
https://www.ncbi.nlm.nih.gov/pubmed/35056126
http://dx.doi.org/10.3390/ph15010068