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Repositioning of Etravirine as a Potential CK1ε Inhibitor by Virtual Screening

CK1ε is a key regulator of WNT/β-catenin and other pathways that are linked to tumor progression; thus, CK1ε is considered a target for the development of antineoplastic therapies. In this study, we performed a virtual screening to search for potential CK1ε inhibitors. First, we characterized the dy...

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Detalles Bibliográficos
Autores principales: Córdova-Bahena, Luis, Sánchez-Álvarez, Axel A., Ruiz-Moreno, Angel J., Velasco-Velázquez, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778358/
https://www.ncbi.nlm.nih.gov/pubmed/35056065
http://dx.doi.org/10.3390/ph15010008