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Repositioning of Etravirine as a Potential CK1ε Inhibitor by Virtual Screening
CK1ε is a key regulator of WNT/β-catenin and other pathways that are linked to tumor progression; thus, CK1ε is considered a target for the development of antineoplastic therapies. In this study, we performed a virtual screening to search for potential CK1ε inhibitors. First, we characterized the dy...
Autores principales: | Córdova-Bahena, Luis, Sánchez-Álvarez, Axel A., Ruiz-Moreno, Angel J., Velasco-Velázquez, Marco A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778358/ https://www.ncbi.nlm.nih.gov/pubmed/35056065 http://dx.doi.org/10.3390/ph15010008 |
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