Determination of Oxaliplatin by a UHPLC-MS/MS Method: Application to Pharmacokinetics and Tongue Tissue Distribution Studies in Rats

Oxaliplatin (OXP), a third-generation platinum-based chemotherapy drug, was often indirectly analyzed via total platinum by an ICP-MS because it was difficult to directly quantify using an LC-MS/MS method, due to its instability, bad column separability and severe MS signal inhibition. Here, we deve...

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Detalles Bibliográficos
Autores principales: Gao, Xiuqing, Tsai, Robert Y. L., Ma, Jing, Wang, Yang, Liu, Xiaohua, Liang, Dong, Xie, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778379/
https://www.ncbi.nlm.nih.gov/pubmed/35056109
http://dx.doi.org/10.3390/ph15010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778379/
https://www.ncbi.nlm.nih.gov/pubmed/35056109
http://dx.doi.org/10.3390/ph15010052

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