SGC-CK2-1 Is an Efficient Inducer of Insulin Production and Secretion in Pancreatic β-Cells

The pyrazolopyrimidine based compound SGC-CK2-1 is a potent and highly specific CK2 inhibitor and a new tool to study the biological functions of protein kinase CK2 irrespective from off-target effects. We used this compound in comparison with the well-established CK2 inhibitor CX-4945 to analyze th...

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Detalles Bibliográficos
Autores principales: Pack, Mandy, Götz, Claudia, Wrublewsky, Selina, Montenarh, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778508/
https://www.ncbi.nlm.nih.gov/pubmed/35056914
http://dx.doi.org/10.3390/pharmaceutics14010019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778508/
https://www.ncbi.nlm.nih.gov/pubmed/35056914
http://dx.doi.org/10.3390/pharmaceutics14010019

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