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Granulocyte Macrophage-Colony Stimulating Factor Produces a Splenic Subset of Monocyte-Derived Dendritic Cells That Efficiently Polarize T Helper Type 2 Cells in Response to Blood-Borne Antigen

Dendritic cells (DCs) are key antigen-presenting cells that prime naive T cells and initiate adaptive immunity. Although the genetic deficiency and transgenic overexpression of granulocyte macrophage-colony stimulating factor (GM-CSF) signaling were reported to influence the homeostasis of DCs, the...

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Detalles Bibliográficos
Autores principales: Ryu, Seul Hye, Shin, Hyun Soo, Eum, Hye Hyeon, Park, Ji Soo, Choi, Wanho, Na, Hye Young, In, Hyunju, Kim, Tae-Gyun, Park, Sejung, Hwang, Soomin, Sohn, Moah, Kim, Eun-Do, Seo, Kyoung Yul, Lee, Hae-Ock, Lee, Min-Geol, Chu, Min Kyung, Park, Chae Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778578/
https://www.ncbi.nlm.nih.gov/pubmed/35069539
http://dx.doi.org/10.3389/fimmu.2021.767037