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Interplay Between Duration of Androgen Deprivation Therapy and External Beam Radiotherapy With or Without a Brachytherapy Boost for Optimal Treatment of High-risk Prostate Cancer: A Patient-Level Data Analysis of 3 Cohorts

IMPORTANCE: Radiotherapy combined with androgen deprivation therapy (ADT) is a standard of care for high-risk prostate cancer. However, the interplay between radiotherapy dose and the required minimum duration of ADT is uncertain. OBJECTIVE: To determine the specific ADT duration threshold that prov...

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Detalles Bibliográficos
Autores principales: Kishan, Amar U., Steigler, Alison, Denham, James W., Zapatero, Almudena, Guerrero, Araceli, Joseph, David, Maldonado, Xavier, Wong, Jessica K., Stish, Bradley J., Dess, Robert T., Pilar, Avinash, Reddy, Chandana, Wedde, Trude B., Lilleby, Wolfgang A., Fiano, Ryan, Merrick, Gregory S., Stock, Richard G., Demanes, D. Jeffrey, Moran, Brian J., Tran, Phuoc T., Martin, Santiago, Martinez-Monge, Rafael, Krauss, Daniel J., Abu-Isa, Eyad I., Pisansky, Thomas M., Choo, C. Richard, Song, Daniel Y., Greco, Stephen, Deville, Curtiland, McNutt, Todd, DeWeese, Theodore L., Ross, Ashley E., Ciezki, Jay P., Tilki, Derya, Karnes, R. Jeffrey, Tosoian, Jeffrey J., Nickols, Nicholas G., Bhat, Prashant, Shabsovich, David, Juarez, Jesus E., Jiang, Tommy, Ma, T. Martin, Xiang, Michael, Philipson, Rebecca, Chang, Albert, Kupelian, Patrick A., Rettig, Matthew B., Feng, Felix Y., Berlin, Alejandro, Tward, Jonathan D., Davis, Brian J., Reiter, Robert E., Steinberg, Michael L., Elashoff, David, Boutros, Paul C., Horwitz, Eric M., Tendulkar, Rahul D., Spratt, Daniel E., Romero, Tahmineh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778608/
https://www.ncbi.nlm.nih.gov/pubmed/35050303
http://dx.doi.org/10.1001/jamaoncol.2021.6871