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B7-H3 promotes the epithelial-mesenchymal transition of NSCLC by targeting SIRT1 through the PI3K/AKT pathway

Epithelial-mesenchymal transition (EMT) is a key step in cancer metastasis. B7-H3, a co-signaling molecule associated with poor prognosis of non-small cell lung cancer (NSCLC), promotes the metastasis of NSCLC by activating the EMT process. However, its underlying mechanism remains poorly understood...

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Detalles Bibliográficos
Autores principales: Liao, Haixiu, Ding, Meng, Zhou, Nannan, Yang, Ying, Chen, Liwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778653/
https://www.ncbi.nlm.nih.gov/pubmed/35029291
http://dx.doi.org/10.3892/mmr.2022.12595