Cargando…

Strain-Promoted Azide–Alkyne Cycloaddition-Based PSMA-Targeting Ligands for Multimodal Intraoperative Tumor Detection of Prostate Cancer

[Image: see text] Strain-promoted azide–alkyne cycloaddition (SPAAC) is a straightforward and multipurpose conjugation strategy. The use of SPAAC to link different functional elements to prostate-specific membrane antigen (PSMA) ligands would facilitate the development of a modular platform for PSMA...

Descripción completa

Detalles Bibliográficos
Autores principales: Derks, Yvonne H. W., Rijpkema, Mark, Amatdjais-Groenen, Helene I. V., Loeff, Cato C., de Roode, Kim E., Kip, Annemarie, Laverman, Peter, Lütje, Susanne, Heskamp, Sandra, Löwik, Dennis W. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778659/
https://www.ncbi.nlm.nih.gov/pubmed/34957825
http://dx.doi.org/10.1021/acs.bioconjchem.1c00537