Identification of an Orally Bioavailable, Brain-Penetrant Compound with Selectivity for the Cannabinoid Type 2 Receptor

Modulation of the endocannabinoid system (ECS) is of great interest for its therapeutic relevance in several pathophysiological processes. The CB2 subtype is largely localized to immune effectors, including microglia within the central nervous system, where it promotes anti-inflammation. Recently, a...

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Detalles Bibliográficos
Autores principales: Ospanov, Meirambek, Sulochana, Suresh P., Paris, Jason J., Rimoldi, John M., Ashpole, Nicole, Walker, Larry, Ross, Samir A., Shilabin, Abbas G., Ibrahim, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778670/
https://www.ncbi.nlm.nih.gov/pubmed/35056824
http://dx.doi.org/10.3390/molecules27020509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778670/
https://www.ncbi.nlm.nih.gov/pubmed/35056824
http://dx.doi.org/10.3390/molecules27020509

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