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Modeling SARS-CoV-2 Infection in Mice Using Lentiviral hACE2 Vectors Infers Two Modes of Immune Responses to SARS-CoV-2 Infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a severe global pandemic. Mice models are essential to investigate infection pathology, antiviral drugs, and vaccine development. However, wild-type mice lack the human angiotensin-converting enzyme 2 (hACE2) that mediates SARS-CoV-...

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Detalles Bibliográficos
Autores principales:	Katzman, Chaja, Israely, Tomer, Melamed, Sharon, Politi, Boaz, Sittner, Assa, Yahalom-Ronen, Yfat, Weiss, Shay, Abu Rass, Reem, Zamostiano, Rachel, Bacharach, Eran, Ehrlich, Marcelo, Paran, Nir, Nissim, Lior
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778683/ https://www.ncbi.nlm.nih.gov/pubmed/35062215 http://dx.doi.org/10.3390/v14010011

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