Cargando…

Overexpression of BQ323636.1 Modulated AR/IL-8/CXCR1 Axis to Confer Tamoxifen Resistance in ER-Positive Breast Cancer

NCOR2 is a co-repressor for estrogen receptor (ER) and androgen receptor (AR). Our group previously identified a novel splice variant of NCOR2, BQ323636.1 (BQ), that mediates tamoxifen resistance via interference of NCOR2 repression on ER. Luciferase reporter assay showed BQ overexpression could enh...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsoi, Ho, Shi, Ling, Leung, Man-Hong, Man, Ellen P. S., So, Zi-Qing, Chan, Wing-Lok, Khoo, Ui-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778777/
https://www.ncbi.nlm.nih.gov/pubmed/35054486
http://dx.doi.org/10.3390/life12010093