Synthesis and Biological Investigation of Bile Acid-Paclitaxel Hybrids

Chenodeoxycholic acid and ursodeoxycholic acid (CDCA and UDCA, respectively) have been conjugated with paclitaxel (PTX) anticancer drugs through a high-yield condensation reaction. Bile acid-PTX hybrids (BA-PTX) have been investigated for their pro-apoptotic activity towards a selection of cancer ce...

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Detalles Bibliográficos
Autores principales: Melloni, Elisabetta, Marchesi, Elena, Preti, Lorenzo, Casciano, Fabio, Rimondi, Erika, Romani, Arianna, Secchiero, Paola, Navacchia, Maria Luisa, Perrone, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779069/
https://www.ncbi.nlm.nih.gov/pubmed/35056786
http://dx.doi.org/10.3390/molecules27020471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779069/
https://www.ncbi.nlm.nih.gov/pubmed/35056786
http://dx.doi.org/10.3390/molecules27020471

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