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Synthesis and Biological Investigation of Bile Acid-Paclitaxel Hybrids

Chenodeoxycholic acid and ursodeoxycholic acid (CDCA and UDCA, respectively) have been conjugated with paclitaxel (PTX) anticancer drugs through a high-yield condensation reaction. Bile acid-PTX hybrids (BA-PTX) have been investigated for their pro-apoptotic activity towards a selection of cancer ce...

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Detalles Bibliográficos
Autores principales:	Melloni, Elisabetta, Marchesi, Elena, Preti, Lorenzo, Casciano, Fabio, Rimondi, Erika, Romani, Arianna, Secchiero, Paola, Navacchia, Maria Luisa, Perrone, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779069/ https://www.ncbi.nlm.nih.gov/pubmed/35056786 http://dx.doi.org/10.3390/molecules27020471

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