Precise Dosing of Pramipexole for Low-Dosed Filament Production by Hot Melt Extrusion Applying Various Feeding Methods

The aim of this research was the production of low-dosed filaments via hot-melt extrusion (HME) with the model drug pramipexole for the treatment of Parkinson’s disease. The active pharmaceutical ingredient (API) and one of the polymers polyvinyl alcohol (PVA) or basic butylated methacrylate copolym...

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Detalles Bibliográficos
Autores principales: Chamberlain, Rebecca, Windolf, Hellen, Geissler, Simon, Quodbach, Julian, Breitkreutz, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779137/
https://www.ncbi.nlm.nih.gov/pubmed/35057112
http://dx.doi.org/10.3390/pharmaceutics14010216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779137/
https://www.ncbi.nlm.nih.gov/pubmed/35057112
http://dx.doi.org/10.3390/pharmaceutics14010216

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