Let-7i-5p Mediates the Therapeutic Effects of Exosomes from Human Placenta Choriodecidual Membrane-Derived Mesenchymal Stem Cells on Mitigating Endotoxin-Induced Mortality and Liver Injury in High-Fat Diet-Induced Obese Mice

Obesity complicates sepsis and increases the mortality of sepsis. We examined the effects of exosomes (from human placenta choriodecidual membrane-derived mesenchymal stem cells, pcMSCs) on preventing sepsis in obesity and the mitigating role of hsa-let-7i-5p microRNA. Obese mice (adult male C57BL/6...

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Detalles Bibliográficos
Autores principales: Chang, Chao-Yuan, Chen, Kung-Yen, Shih, Hung-Jen, Chiang, Milton, Huang, I-Tao, Huang, Yen-Hua, Huang, Chun-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779189/
https://www.ncbi.nlm.nih.gov/pubmed/35056093
http://dx.doi.org/10.3390/ph15010036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779189/
https://www.ncbi.nlm.nih.gov/pubmed/35056093
http://dx.doi.org/10.3390/ph15010036

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