A Surfactant Enables Efficient Membrane Spanning by Non-Aggregating DNA-Based Ion Channels

DNA nanotechnology makes use of hydrophobically modified constructs to create synthetic membrane protein mimics. However, nucleic acid structures exhibit poor insertion efficiency, leading to a low activity of membrane-spanning DNA protein mimics. It is suggested that non-ionic surfactants improve i...

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Detalles Bibliográficos
Autores principales: Morzy, Diana, Schaich, Michael, Keyser, Ulrich F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779190/
https://www.ncbi.nlm.nih.gov/pubmed/35056887
http://dx.doi.org/10.3390/molecules27020578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779190/
https://www.ncbi.nlm.nih.gov/pubmed/35056887
http://dx.doi.org/10.3390/molecules27020578

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