Determining the Anticancer Activity of Sphingosine Kinase Inhibitors Containing Heteroatoms in Their Tail Structure

Sphingosine kinase (SK) enzyme, a central player of sphingolipid rheostat, catalyzes the phosphorylation of sphingosine to the bioactive lipid mediator sphingosine 1 phosphate (S1P), which regulates cancer cell proliferation, migration, differentiation, and angiogenesis through its extracellular fiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Shrestha, Jitendra, Kim, Seong Woong, Kim, Su-Bin, Oh, Yoon Sin, Ki, Sung Hwan, Lee, Taeho, Kim, Sang-Bum, Park, Taeuk, Baek, Dong Jae, Park, Eun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779255/
https://www.ncbi.nlm.nih.gov/pubmed/35057052
http://dx.doi.org/10.3390/pharmaceutics14010157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779255/
https://www.ncbi.nlm.nih.gov/pubmed/35057052
http://dx.doi.org/10.3390/pharmaceutics14010157

Ejemplares similares