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Determining the Anticancer Activity of Sphingosine Kinase Inhibitors Containing Heteroatoms in Their Tail Structure

Sphingosine kinase (SK) enzyme, a central player of sphingolipid rheostat, catalyzes the phosphorylation of sphingosine to the bioactive lipid mediator sphingosine 1 phosphate (S1P), which regulates cancer cell proliferation, migration, differentiation, and angiogenesis through its extracellular fiv...

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Detalles Bibliográficos
Autores principales:	Shrestha, Jitendra, Kim, Seong Woong, Kim, Su-Bin, Oh, Yoon Sin, Ki, Sung Hwan, Lee, Taeho, Kim, Sang-Bum, Park, Taeuk, Baek, Dong Jae, Park, Eun-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779255/ https://www.ncbi.nlm.nih.gov/pubmed/35057052 http://dx.doi.org/10.3390/pharmaceutics14010157

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