Comparison of an Addictive Potential of μ-Opioid Receptor Agonists with G Protein Bias: Behavioral and Molecular Modeling Studies

Among different approaches to the search for novel—safer and less addictive—opioid analgesics, biased agonism has received the most attention in recent years. Some μ-opioid receptor agonists with G protein bias, including SR compounds, were proposed to induce diminished side effects. However, in man...

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Detalles Bibliográficos
Autores principales: Kudla, Lucja, Bugno, Ryszard, Podlewska, Sabina, Szumiec, Lukasz, Wiktorowska, Lucja, Bojarski, Andrzej J., Przewlocki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779292/
https://www.ncbi.nlm.nih.gov/pubmed/35056950
http://dx.doi.org/10.3390/pharmaceutics14010055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779292/
https://www.ncbi.nlm.nih.gov/pubmed/35056950
http://dx.doi.org/10.3390/pharmaceutics14010055

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