Synthesis, Physicochemical and Biological Study of Gallium-68- and Lutetium-177-Labeled VEGF-A(165)/NRP-1 Complex Inhibitors Based on Peptide A7R and Branched Peptidomimetic

Neuropilin-1 (NRP-1) is a surface receptor found on many types of cancer cells. The overexpression of NRP-1 and its interaction with vascular endothelial growth factor-165 (VEGF(165)) are associated with tumor growth and metastasis. Therefore, compounds that block the VEGF(165)/NRP-1 interaction rep...

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Detalles Bibliográficos
Autores principales: Masłowska, Katarzyna, Witkowska, Ewa, Tymecka, Dagmara, Halik, Paweł Krzysztof, Misicka, Aleksandra, Gniazdowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779334/
https://www.ncbi.nlm.nih.gov/pubmed/35056995
http://dx.doi.org/10.3390/pharmaceutics14010100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779334/
https://www.ncbi.nlm.nih.gov/pubmed/35056995
http://dx.doi.org/10.3390/pharmaceutics14010100

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