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Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models

Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant improvements in the last two decades, and novel effective treatments are needed. OS in companion dogs is phenotypically close to human OS, which makes a comparative oncology approach to developing new trea...

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Detalles Bibliográficos
Autores principales: Broqueza, Jaline, Prabaharan, Chandra B., Allen, Kevin J. H., Jiao, Rubin, Fisher, Darrell R., Dickinson, Ryan, MacDonald-Dickinson, Valerie, Uppalapati, Maruti, Dadachova, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779382/
https://www.ncbi.nlm.nih.gov/pubmed/35056067
http://dx.doi.org/10.3390/ph15010010