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TYMS 3′-UTR Polymorphism: A Novel Association with FOLFIRINOX-Induced Neurotoxicity in Pancreatic Cancer Patients

Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that has the worst 5-year survival rate of all of the common malignant tumors. Surgery, chemotherapy, and/or chemoradiation remain the main tactics for PDAC treatment. The efficacy of chemotherapy is often compromised because of th...

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Detalles Bibliográficos
Autores principales: Emelyanova, Marina, Pokataev, Ilya, Shashkov, Igor, Kopantseva, Elena, Lyadov, Vladimir, Heydarov, Rustam, Mikhailovich, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779442/
https://www.ncbi.nlm.nih.gov/pubmed/35056973
http://dx.doi.org/10.3390/pharmaceutics14010077