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Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics

The neonatal mammalian heart exhibits a remarkable regenerative potential, which includes fibrotic scar resolution and the generation of new cardiomyocytes. To investigate the mechanisms facilitating heart repair after apical resection in neonatal mice, we conducted bulk and spatial transcriptomic a...

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Detalles Bibliográficos
Autores principales: Misra, Adwiteeya, Baker, Cameron D., Pritchett, Elizabeth M., Burgos Villar, Kimberly N., Ashton, John M., Small, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779463/
https://www.ncbi.nlm.nih.gov/pubmed/35050211
http://dx.doi.org/10.3390/jcdd9010001