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Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is a life-threatening form of heart disease that is typically characterized by progressive thinning of the ventricular walls, chamber dilation, and systolic dysfunction. Multiple mutations in the gene encoding filamin C (FLNC), an actin-binding cytoskeletal protein in ca...

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Detalles Bibliográficos
Autores principales: Powers, Joseph D., Kirkland, Natalie J., Liu, Canzhao, Razu, Swithin S., Fang, Xi, Engler, Adam J., Chen, Ju, McCulloch, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779483/
https://www.ncbi.nlm.nih.gov/pubmed/35055055
http://dx.doi.org/10.3390/ijms23020871