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Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a life-threatening form of heart disease that is typically characterized by progressive thinning of the ventricular walls, chamber dilation, and systolic dysfunction. Multiple mutations in the gene encoding filamin C (FLNC), an actin-binding cytoskeletal protein in ca...
Autores principales: | Powers, Joseph D., Kirkland, Natalie J., Liu, Canzhao, Razu, Swithin S., Fang, Xi, Engler, Adam J., Chen, Ju, McCulloch, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779483/ https://www.ncbi.nlm.nih.gov/pubmed/35055055 http://dx.doi.org/10.3390/ijms23020871 |
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