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Endogenous Nitric Oxide-Releasing Microgel Coating Prevents Clot Formation on Oxygenator Fibers Exposed to In Vitro Blood Flow

Background: Clot formation on foreign surfaces of extracorporeal membrane oxygenation systems is a frequent event. Herein, we show an approach that mimics the enzymatic process of endogenous nitric oxide (NO) release on the oxygenator membrane via a biomimetic, non-fouling microgel coating to spatio...

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Detalles Bibliográficos
Autores principales: Winnersbach, Patrick, Hosseinnejad, Aisa, Breuer, Thomas, Fechter, Tamara, Jakob, Felix, Schwaneberg, Ulrich, Rossaint, Rolf, Bleilevens, Christian, Singh, Smriti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779597/
https://www.ncbi.nlm.nih.gov/pubmed/35054599
http://dx.doi.org/10.3390/membranes12010073