XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine

Whilst avoidance of chemical modifications of DNA bases is essential to maintain genome stability, during evolution eukaryotic cells have evolved a chemically reversible modification of the cytosine base. These dynamic methylation and demethylation reactions on carbon-5 of cytosine regulate several...

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Detalles Bibliográficos
Autores principales: Peña-Gómez, María José, Suárez-Pizarro, Marina, Rosado, Iván V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779622/
https://www.ncbi.nlm.nih.gov/pubmed/35055077
http://dx.doi.org/10.3390/ijms23020893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779622/
https://www.ncbi.nlm.nih.gov/pubmed/35055077
http://dx.doi.org/10.3390/ijms23020893

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