Overcoming MDR by Associating Doxorubicin and pH-Sensitive PLGA Nanoparticles Containing a Novel Organoselenium Compound—An In Vitro Study

In this study, we developed PLGA nanoparticles (NPs) as an effective carrier for 5′-Se-(phenyl)-3-(amino)-thymidine (ACAT-Se), an organoselenium compound, nucleoside analogue that showed promising antitumor activity in vitro. The PLGA NPs were prepared by the nanoprecipitation method and modified wi...

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Detalles Bibliográficos
Autores principales: Macedo, Letícia Bueno, Nogueira-Librelotto, Daniele Rubert, Mathes, Daniela, de Vargas, Josiele Melo, da Rosa, Raquel Mello, Rodrigues, Oscar Endrigo Dorneles, Vinardell, Maria Pilar, Mitjans, Montserrat, Rolim, Clarice Madalena Bueno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779681/
https://www.ncbi.nlm.nih.gov/pubmed/35056975
http://dx.doi.org/10.3390/pharmaceutics14010080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779681/
https://www.ncbi.nlm.nih.gov/pubmed/35056975
http://dx.doi.org/10.3390/pharmaceutics14010080

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