A Tear Metabolomic Profile Showing Increased Ornithine Decarboxylase Activity and Spermine Synthesis in Thyroid-Associated Orbitopathy

About half of patients with Graves’ disease develop an orbitopathy related to an inflammatory expansion of the periorbital adipose tissue and muscles. We used a targeted metabolomic approach measuring 188 metabolites by mass spectrometry to compare the metabolic composition of tears in patients with...

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Detalles Bibliográficos
Autores principales: Billiet, Benjamin, Chao de la Barca, Juan Manuel, Ferré, Marc, Muller, Jeanne, Vautier, Anaïs, Assad, Sophie, Blanchet, Odile, Tessier, Lydie, Wetterwald, Céline, Faure, Justine, Urbanski, Geoffrey, Simard, Gilles, Mirebeau-Prunier, Delphine, Rodien, Patrice, Gohier, Philippe, Reynier, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779711/
https://www.ncbi.nlm.nih.gov/pubmed/35054098
http://dx.doi.org/10.3390/jcm11020404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779711/
https://www.ncbi.nlm.nih.gov/pubmed/35054098
http://dx.doi.org/10.3390/jcm11020404

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