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Crosslinking-Dependent Drug Kinetics in Hydrogels for Ophthalmic Delivery

Drug-diffusion kinetics in 2-hydroxyethyl methacrylate hydrogels were studied as a function of the crosslinking density and porosity. By varying the concentration of the crosslinker, tetraethylene glycol dimethacrylate, we demonstrated how the release of Timolol maleate could be optimized to allow f...

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Detalles Bibliográficos
Autores principales: Mortensen, Nicole, Toews, Parker, Bates, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779755/
https://www.ncbi.nlm.nih.gov/pubmed/35054655
http://dx.doi.org/10.3390/polym14020248