Application of Mathematical Models to Determine the Feasibility of Amorphous Drug Layering in Pan Coaters

Oral solid dosage forms that contain APIs in the amorphous state have become commonplace because of many drug substances exhibiting poor water solubility, which negatively impacts their absorption in the human GI tract. While micronization, solvent spray-drying, and hot-melt extrusion can address so...

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Detalles Bibliográficos
Autores principales: Choi, Michael, Porter, Stuart C., Meisen, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779791/
https://www.ncbi.nlm.nih.gov/pubmed/35057045
http://dx.doi.org/10.3390/pharmaceutics14010149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779791/
https://www.ncbi.nlm.nih.gov/pubmed/35057045
http://dx.doi.org/10.3390/pharmaceutics14010149

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