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Immunity to Sda1 Protects against Infection by Sda1(+) and Sda1(−) Serotypes of Group A Streptococcus

Group A Streptococcus (GAS) causes a variety of diseases globally. The DNases in GAS promote GAS evasion of neutrophil killing by degrading neutrophil extracellular traps (NETs). Sda1 is a prophage-encoded DNase associated with virulent GAS strains. However, protective immunity against Sda1 has not...

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Detalles Bibliográficos
Autores principales: Bi, Shuai, Wang, Jie, Xu, Meiyi, Li, Ning, Wang, Beinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779841/
https://www.ncbi.nlm.nih.gov/pubmed/35062763
http://dx.doi.org/10.3390/vaccines10010102