In Vitro and In Vivo Bioequivalence Study of 3D-Printed Instant-Dissolving Levetiracetam Tablets and Subsequent Personalized Dosing for Chinese Children Based on Physiological Pharmacokinetic Modeling

Recently, the development of Binder Jet 3D printing technology has promoted the research and application of personalized formulations, which are especially useful for children’s medications. Additionally, physiological pharmacokinetic (PBPK) modeling can be used to guide drug development and drug do...

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Detalles Bibliográficos
Autores principales: Li, Xianfu, Liang, En, Hong, Xiaoxuan, Han, Xiaolu, Li, Conghui, Wang, Yuxi, Wang, Zengming, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779920/
https://www.ncbi.nlm.nih.gov/pubmed/35056916
http://dx.doi.org/10.3390/pharmaceutics14010020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779920/
https://www.ncbi.nlm.nih.gov/pubmed/35056916
http://dx.doi.org/10.3390/pharmaceutics14010020

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