New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators

A series of histamine (HST)-related compounds were synthesized and tested for their activating properties on five physiologically relevant human Carbonic Anhydrase (hCA) isoforms (I, II, Va, VII and XIII). The imidazole ring of HST was replaced with different 5-membered heterocycles and the length o...

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Detalles Bibliográficos
Autores principales: Chiaramonte, Niccolò, Gabellini, Alessio, Angeli, Andrea, Bartolucci, Gianluca, Braconi, Laura, Dei, Silvia, Teodori, Elisabetta, Supuran, Claudiu T., Romanelli, Maria Novella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779960/
https://www.ncbi.nlm.nih.gov/pubmed/35056859
http://dx.doi.org/10.3390/molecules27020545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779960/
https://www.ncbi.nlm.nih.gov/pubmed/35056859
http://dx.doi.org/10.3390/molecules27020545

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