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Matrix stiffness mechanosensing modulates the expression and distribution of transcription factors in Schwann cells

After peripheral nerve injury, mature Schwann cells (SCs) de‐differentiate and undergo cell reprogramming to convert into a specialized cell repair phenotype that promotes nerve regeneration. Reprogramming of SCs into the repair phenotype is tightly controlled at the genome level and includes downre...

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Detalles Bibliográficos
Autores principales: Rosso, Gonzalo, Wehner, Daniel, Schweitzer, Christine, Möllmert, Stephanie, Sock, Elisabeth, Guck, Jochen, Shahin, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780053/
https://www.ncbi.nlm.nih.gov/pubmed/35079632
http://dx.doi.org/10.1002/btm2.10257