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Improved Release of a Drug with Poor Water Solubility by Using Electrospun Water-Soluble Polymers as Carriers

In an attempt to improve the solubility of valsartan, a BCS II drug, fibers containing the drug were prepared from three water-soluble polymers, hydroxypropyl-methyl-cellulose (HPMC), polyvinyl-pyrrolidone (PVP), and polyvinyl-alcohol (PVA). Fiber spinning technology was optimized for each polymer s...

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Detalles Bibliográficos
Autores principales: Józó, Muriel, Simon, Nóra, Yi, Lan, Móczó, János, Pukánszky, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780061/
https://www.ncbi.nlm.nih.gov/pubmed/35056930
http://dx.doi.org/10.3390/pharmaceutics14010034