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Improved Release of a Drug with Poor Water Solubility by Using Electrospun Water-Soluble Polymers as Carriers
In an attempt to improve the solubility of valsartan, a BCS II drug, fibers containing the drug were prepared from three water-soluble polymers, hydroxypropyl-methyl-cellulose (HPMC), polyvinyl-pyrrolidone (PVP), and polyvinyl-alcohol (PVA). Fiber spinning technology was optimized for each polymer s...
Autores principales: | Józó, Muriel, Simon, Nóra, Yi, Lan, Móczó, János, Pukánszky, Béla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780061/ https://www.ncbi.nlm.nih.gov/pubmed/35056930 http://dx.doi.org/10.3390/pharmaceutics14010034 |
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