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Long‐acting and extended‐release implant and nanoformulations with a synergistic antiretroviral two‐drug combination controls HIV‐1 infection in a humanized mouse model

The HIV pandemic has affected over 38 million people worldwide with close to 26 million currently accessing antiretroviral therapy (ART). A major challenge in the long‐term treatment of HIV‐1 infection is nonadherence to ART. Long‐acting antiretroviral (LA‐ARV) formulations, that reduce dosing frequ...

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Detalles Bibliográficos
Autores principales: Beloor, Jagadish, Kudalkar, Shalley N., Buzzelli, Gina, Yang, Fan, Mandl, Hanna K., Rajashekar, Jyothi K., Spasov, Krasimir A., Jorgensen, William L., Saltzman, W. Mark, Anderson, Karen S., Kumar, Priti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780078/
https://www.ncbi.nlm.nih.gov/pubmed/35079625
http://dx.doi.org/10.1002/btm2.10237